Goalkeepers
| # | Player | Club | Age | Caps | Goals |
|---|
| 1 | Matt Turner | New England Revolution | 31 | 54 | 0 |
| 24 | Matt Freese | New York City FC | 27 | 15 | 0 |
| 25 | Chris Brady | Chicago Fire FC | 22 | 1 | 0 |
Defenders
| # | Player | Club | Age | Caps | Goals |
|---|
| 2 | Sergiño Dest | PSV Eindhoven | 25 | 39 | 3 |
| 3 | Chris Richards | Crystal Palace | 26 | 36 | 3 |
| 5 | Antonee Robinson | Fulham | 28 | 54 | 5 |
| 6 | Auston Trusty | Celtic | 27 | 8 | 0 |
| 12 | Miles Robinson | FC Cincinnati | 29 | 40 | 3 |
| 13 | Tim ReamC | Charlotte FC | 38 | 82 | 1 |
| 16 | Alex Freeman | Villarreal | 21 | 17 | 2 |
| 18 | Max Arfsten | Columbus Crew | 25 | 20 | 1 |
| 22 | Mark McKenzie | Toulouse | 27 | 29 | 0 |
| 23 | Joe Scally | Borussia Mönchengladbach | 23 | 26 | 0 |
Midfielders
| # | Player | Club | Age | Caps | Goals |
|---|
| 4 | Tyler Adams | Bournemouth | 27 | 54 | 2 |
| 7 | Giovanni Reyna | Borussia Mönchengladbach | 23 | 38 | 9 |
| 8 | Weston McKennie | Juventus | 27 | 66 | 12 |
| 14 | Sebastian Berhalter | Vancouver Whitecaps FC | 25 | 13 | 1 |
| 15 | Cristian Roldan | Seattle Sounders FC | 31 | 47 | 0 |
| 17 | Malik Tillman | Bayer Leverkusen | 24 | 30 | 3 |
Forwards
| # | Player | Club | Age | Caps | Goals |
|---|
| 9 | Ricardo Pepi | PSV Eindhoven | 23 | 37 | 13 |
| 10 | Christian Pulisic | Milan | 27 | 86 | 33 |
| 11 | Brenden Aaronson | Leeds United | 25 | 58 | 9 |
| 19 | Haji Wright | Coventry City | 28 | 20 | 7 |
| 20 | Folarin Balogun | Monaco | 24 | 27 | 9 |
| 21 | Timothy Weah | Marseille | 26 | 51 | 7 |
| 26 | Alejandro Zendejas | América | 28 | 14 | 2 |
USAUnited States